Recent publications

Mahadevan, J., Pathak, A. K., Vemula, A., Nadella, R. K., Viswanath, B., Jain, S., Rao, N. P., Narayanaswamy, J. C., Viswanath, B., Sivakumar, P. T., Kandasamy, A., Kesavan, M., Mehta, U. M., Venkatasubramanian, G., John, J. P., Purushottam, M., Mukherjee, O., Kannan, R., Mehta, B., … Accelerator Program for Discovery in Brain disorders using Stem cells (ADBS) Consortium. (2021). Analysis of whole exome sequencing in severe mental illness hints at selection of brain development and immune related genes. Scientific Reports, 11(1), 21088.
https://doi.org/10.1038/s41598-021-00123-x

Sakhardande, K. A., Reddi, V. S. K., Mishra, S., Navin, K., Ramu, A., Arunachal, G., Mangalore, S., Yadav, R., & Jain, S. (2021). Homozygous PLA2G6 (PARK 14) gene mutation associated neuropsychiatric phenotypes from southern India. Parkinsonism & Related Disorders, 90, 49–51. https://doi.org/10.1016/j.parkreldis.2021.07.026

Ithal, D., Sukumaran, S. K., Bhattacharjee, D., Vemula, A., Nadella, R., Mahadevan, J., Sud, R., Viswanath, B., Purushottam, M., & Jain, S. (2021). Exome hits demystified: the next frontier. Asian Journal of Psychiatry, 102640. https://doi.org/10.1016/j.ajp.2021.102640

Manjappa, P., Balachander, S., Naaz, S., Nadella, R. K., Shukla, T., Paul, P., Purushottam, M., Janardhan Reddy, Y. C., Jain, S., Viswanath, B., & Sud, R. (2021). Cell cycle abnormality is a cellular phenotype in OCD. Asian Journal of Psychiatry, 59, 102637.
https://doi.org/10.1016/j.ajp.2021.102637

Mahadevan, J., Sud, R., Nadella, R. K., Vani, P., Subramaniam, A. G., Paul, P., Ganapathy, A., Mannan, A. U., Chandru, V., Viswanath, B., Purushottam, M., & Jain, S. (2021). Targeted Sequencing Detects Variants That May Contribute to the Risk of Neuropsychiatric Disorders. Indian Journal of Psychological Medicine, 025371762199367.
https://doi.org/10.1177/0253717621993672

Soundararajan, S., Agrawal, A., Purushottam, M., Anand, S. D., Shankarappa, B., Sharma, P., Jain, S., & Murthy, P. (2021). Changes in DNA methylation persist over time in males with severe alcohol use disorder-A longitudinal follow-up study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics. https://doi.org/10.1002/ajmg.b.32833

Paul, P., Nadella, R. K., Viswanath, B., Reddy, Y. C. J., Jain, S., & Purushottam, M. (2021). Does CACNA1C rs1006737 genotype play a role in lithium treatment response in bipolar disorder patients? Asian Journal of Psychiatry, 56, 102525. https://doi.org/10.1016/j.ajp.2020.102525

Paul, P., Iyer, S., Nadella, R. K., Nayak, R., Chellappa, A. S., Ambardar, S., Sud, R., Sukumaran, S. K., Purushottam, M., Jain, S., ADBS Consortium (ADBS: The Accelerator program for Discovery in Brain disorders using Stem cells), & Viswanath, B. (2020). Lithium response in bipolar disorder correlates with improved cell viability of patient derived cell lines. Scientific Reports, 10(1), 7428. https://doi.org/10.1038/s41598-020-64202-1

Ratna, N., Kamble, N. L., Venkatesh, S. D., Purushottam, M., Pal, P. K., & Jain, S. (2020). Psychiatric morbidity and poor follow-up underlie suboptimal functional and survival outcomes in Huntington’s disease. BMC Neurology, 20(1), 87. https://doi.org/10.1186/s12883-020-01671-x

Shukla, T., Nadella, R. K., Taj M J, R. J., Ganesh, S., Nestadt, G., Purushottam, M., Jain, S., Reddy, Y. C. J., & Viswanath, B. (2020). Association of SLC1A1 gene polymorphism with obsessive compulsive disorder in a sample from southern India. Experimental and Clinical Psychopharmacology, 28(6), 617–621. https://doi.org/10.1037/pha0000348

Naaz, S., Balachander, S., Srinivasa Murthy, N., Ms, B., Sud, R., Saha, P., Narayanaswamy, J. C., Reddy Yc, J., Jain, S., Purushottam, M., & Viswanath, B. (2020). Association of SAPAP3 allelic variants with symptom dimensions and pharmacological treatment response in obsessive-compulsive disorder. Experimental and Clinical Psychopharmacology.
https://doi.org/10.1037/pha0000422

Mahadevan, J., Sud, R., Nadella, R. K., P, V., Subramaniam, A. G., Paul, P., G, A., Mannan, A. U., Chandru, V., Purushottam, M., Viswanath, B., & Jain, S. (2020). An audit and insights from clinical exome sequencing in psychiatry: genotype-phenotype correlation [Preprint]. Open Science Framework. https://doi.org/10.31219/osf.io/5fu6t

Anjanappa, R. M., Nayak, S., Moily, N. S., Manduva, V., Nadella, R. K., Viswanath, B., Reddy, Y. C. J., Jain, S., & Anand, A. (2020). A linkage and exome study implicates rare variants of KANK4 and CAP2 in bipolar disorder in a multiplex family. Bipolar Disorders, 22(1), 70–78.
https://doi.org/10.1111/bdi.12815

Holla, B., Dayal, P., Das, A., Bhattacharya, M., Manjula, V., Ithal, D., Balachander, S., Mahadevan, J., Nadella, R. K., Sreeraj, V. S., Benegal, V., Reddy, J. Y. C., Mehta, U. M., Viswanath, B., & ADBS Consortium. (2020). Transdiagnostic neurocognitive endophenotypes in major psychiatric illness [Preprint]. medRxiv. https://doi.org/10.1101/2020.02.14.20022863

Paul, P., Iyer, S., Nadella, R. K., Nayak, R., Chellappa, A. S., Ambardar, S., Sud, R., Sukumaran, S. K., Purushottam, M., Jain, S., & Viswanath, B. (2020). Lithium response in bipolar disorder correlates with improved cell viability of patient derived cell lines. Scientific Reports, 10(1), 1–10. https://doi.org/10.1038/s41598-020-64202-1

Nadella, R. K., Chellappa, A., Subramaniam, A. G., More, R. P., Shetty, S., Prakash, S., Ratna, N., Vandana, V. P., Purushottam, M., Saini, J., Viswanath, B., Bindu, P. S., Nagappa, M., Mehta, B., Jain, S., & Kannan, R. (2019). Identification and functional characterization of two novel mutations in KCNJ10 and PI4KB in SeSAME syndrome without electrolyte imbalance. Human Genomics, 13(1), 53. https://doi.org/10.1186/s40246-019-0236-0

Anjanappa, R. M., Jain, S., Wali, G. M., & Purushottam, M. (2019). Genetic analysis of a family from India with Machado-Joseph disease. Neurology India, 67(2), 582–588.
https://doi.org/10.4103/0028-3886.258030

Timothy, A., Benegal, V., Shankarappa, B., Saxena, S., Jain, S., & Purushottam, M. (2019). Influence of early adversity on cortisol reactivity, SLC6A4 methylation and externalizing behavior in children of alcoholics. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 94, 109649. https://doi.org/10.1016/j.pnpbp.2019.109649

Ahmed P H, V V, More RP, Viswanath B, Jain S, Rao MS, Mukherjee O; ADBS Consortium.. INDEX-db: The Indian Exome Reference Database (Phase I). J Comput Biol. 2019 Mar;26(3):225-234. doi: 10.1089/cmb.2018.0199. Epub 2019 Jan 7. PubMed PMID: 30615482.

Ashok A, Naaz S, Kota LN, Sen S, Purushottam M, Faruq M, Kumari R, Yadav V, Kannan R, Jain S, Panicker MM, Viswanath B. Does retinoic acid reverse cell cycle dysregulation in Alzheimer's disease lymphocytes? Asian J Psychiatr. 2019 Jan;39:174-177. doi: 10.1016/j.ajp.2018.08.010. Epub 2018 Aug 16. PubMed PMID: 30139662.

Ganesh S, Ahmed P H, Nadella RK, More RP, Seshadri M, Viswanath B, Rao M, Jain S; ADBS Consortium., Mukherjee O. Exome sequencing in families with severe mental illness identifies novel and rare variants in genes implicated in Mendelian neuropsychiatric syndromes. Psychiatry Clin Neurosci. 2019 Jan;73(1):11-19. doi: 10.1111/pcn.12788. Epub 2018 Dec 12. PubMed PMID: 30367527.

Najar AH, Sneha KM, Ashok A, Babu S, Subramaniam AG, Kannan R, Viswanath B, Purushottam M, Varghese M, Parvez S, Panicker MM, Mukherjee O, Jain S. Derivation of iPSC lines from two patients with familial Alzheimer's disease from India. Stem Cell Res. 2019 Jan;34:101370. doi: 10.1016/j.scr.2018.101370. Epub 2018 Dec 19. PubMed PMID: 30605839.

Sathur Raghuraman B, Paul P, Nadella RK, Kapur V, Purushottam M, Jain S, Kannan R, Del Zompo M, Viswanath B. GSK-3b 50 T/C polymorphism in bipolar disorder and its relationship with clinical phenotypes and treatment response. J Affect Disord. 2018 Dec 1;241:433-435. doi: 10.1016/j.jad.2018.08.079. Epub 2018 Aug 17. PubMed PMID: 30145514.

Shere S, Subramanian S, Bharath S, Purushottam M. Lower levels of serum copper in patients with Alzheimer's dementia: A controlled study from India. Asian J Psychiatr. 2018 Feb;32:73-74. doi: 10.1016/j.ajp.2017.11.036. Epub 2017 Dec 2. PubMed PMID: 29220779.

Paul P, Dahale A, Kishore B, Chand P, Benegal V, Jain S, Murthy P, Purushottam M. Association of N-Methyl-D-Aspartate receptor 2B Subunit (GRIN2B) polymorphism with earlier age at onset of withdrawal symptoms in Indian alcohol dependent subjects. J Addict Dis. 2017 Jan-Mar;36(1):48-52. doi: 10.1080/10550887.2016.1140434. Epub 2016 Jan 15. PubMed PMID: 26771436.

Viswanath B, Rao NP, Narayanaswamy JC, Sivakumar PT, Kandasamy A, Kesavan M,Mehta UM, Venkatasubramanian G, John JP, Mukherjee O, Purushottam M, Kannan R,Mehta B, Kandavel T, Binukumar B, Saini J, Jayarajan D, Shyamsundar A,Moirangthem S, Vijay Kumar KG, Thirthalli J, Chandra PS, Gangadhar BN, Murthy P,Panicker MM, Bhalla US, Chattarji S, Benegal V, Varghese M, Reddy JYC, Raghu P,Rao M, Jain S. Discovery biology of neuropsychiatric syndromes (DBNS): a centerfor integrating clinical medicine and basic science. BMC Psychiatry. 2018 Apr18;18(1):106. doi: 10.1186/s12888-018-1674-2. PubMed PMID: 29669557; PubMed Central PMCID: PMC5907468.

Kapur V, Nadella RK, Sathur Raghuraman B, Saraf G, Mishra S, Srinivasmurthy N,Jain S, Del Zompo M, Viswanath B. Clinical factors associated with lithium treatment response in bipolar disorder patients from India. Asian J Psychiatr. 2018 Apr 3. pii: S1876-2018(17)30921-8. doi: 10.1016/j.ajp.2018.04.006. [Epub ahead of print] PubMed PMID: 29636228.

Venkatesh SD, Kandasamy M, Moily NS, Vaidyanathan R, Kota LN, Adhikarla S,Yadav R, Pal PK, Jain S, Purushottam M. Genetic testing for clinically suspected spinocerebellar ataxias: report from a tertiary referral centre in India. JGenet. 2018 Mar;97(1):219-224. PubMed PMID: 29666341.

Syama A, Sen S, Kota LN, Viswanath B, Purushottam M, Varghese M, Jain S, Panicker MM, Mukherjee O. Mutation burden profile in familial Alzheimer's disease cases from India. Neurobiol Aging. 2018 Apr;64:158.e7-158.e13. doi:10.1016/j.neurobiolaging.2017.12.002. Epub 2017 Dec 12. PubMed PMID: 29329714.

Bauer M, Glenn T, Alda M, Aleksandrovich MA, Andreassen OA, Angelopoulos E, Ardau R, Ayhan Y, Baethge C, Bharathram SR, Bauer R, Baune BT, Becerra-Palars C,Bellivier F, Belmaker RH, Berk M, Bersudsky Y, Bicakci S, Birabwa-Oketcho H,Bjella TD, Bossini L, Cabrera J, Cheung EYW, Del Zompo M, Dodd S, Donix M, Etain B, Fagiolini A, Fountoulakis KN, Frye MA, Gonzalez-Pinto A, Gottlieb JF, Grof P, Harima H, Henry C, Isometsä ET, Janno S, Kapczinski F, Kardell M, Khaldi S,Kliwicki S, König B, Kot TL, Krogh R, Kunz M, Lafer B, Landén M, Larsen ER,Lewitzka U, Licht RW, Lopez-Jaramillo C, MacQueen G, Manchia M, Marsh W,Martinez-Cengotitabengoa M, Melle I, Meza-Urzúa F, Yee Ming M, Monteith S, Morken G, Mosca E, Munoz R, Mythri SV, Nacef F, Nadella RK, Nery FG, Nielsen RE,O'Donovan C, Omrani A, Osher Y, Østermark Sørensen H, Ouali U, Pica Ruiz Y,Pilhatsch M, Pinna M, da Ponte FDR, Quiroz D, Ramesar R, Rasgon N, Reddy MS, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Scippa ÂM, Severus E, Simhandl C, Stein DJ, Strejilevich S, Subramaniam M, Sulaiman AH, Suominen K, Tagata H, Tatebayashi Y, Tondo L, Torrent C, Vaaler AE, Veeh J, Vieta E, Viswanath B, Yoldi-Negrete M, Zetin M, Zgueb Y, Whybrow PC. Solar insolation in springtime influences age of onset of bipolar I disorder. Acta Psychiatr Scand. 2017 Dec;136(6):571-582. doi:10.1111/acps.12772. Epub 2017 Jul 19. PubMed PMID: 28722128.

Viswanath B, Mj RJT, Nadella RK, Shukla T, Nanjundaswamy MH, Purushottam M,Janardhan Reddy YC, Jain RS. Does GRIN2B gene influence obsessive-compulsive disorder risk, symptom dimensions and treatment response? Asian J Psychiatr. 2018 Jan;31:150-151. doi: 10.1016/j.ajp.2017.12.013. Epub 2017 Dec 21. PubMed PMID: 29321103.

Taj M J RJ, Ganesh S, Shukla T, Deolankar S, Nadella RK, Sen S, Purushottam M, Reddy YCJ, Jain S, Viswanath B. BDNF gene and obsessive compulsive disorder risk,symptom dimensions and treatment response. Asian J Psychiatr. 2017 Oct 18. pii: S1876-2018(17)30592-0. doi: 10.1016/j.ajp.2017.10.014. [Epub ahead of print] PubMed PMID: 29079096.

Mythri RB, Raghunath NR, Narwade SC, Pandareesh MDR, Sabitha KR, Aiyaz M,Chand B, Sule M, Ghosh K, Kumar S, Shankarappa B, Soundararajan S, Alladi PA,Purushottam M, Gayathri N, Deobagkar DD, Laxmi TR, Srinivas Bharath MM. Manganese- and 1-methyl-4-phenylpyridinium-induced neurotoxicity display differences in morphological, electrophysiological and genome-wide alterations:implications for idiopathic Parkinson's disease. J Neurochem. 2017 Nov;143(3):334-358. doi: 10.1111/jnc.14147. Epub 2017 Oct 3. PubMed PMID: 28801915.

Deepha S, Vengalil S, Preethish-Kumar V, Polavarapu K, Nalini A, Gayathri N,Purushottam M. MLPA identification of dystrophin mutations and in silico evaluation of the predicted protein in dystrophinopathy cases from India. BMC Med Genet. 2017 Jun 13;18(1):67. doi: 10.1186/s12881-017-0431-6. PubMed PMID: 28610567; PubMed Central PMCID: PMC5470271.

Shankarappa BM, Kota LN, Purushottam M, Nagpal K, Mukherjee O, Viswanath B,Varghese M, Bharath S, Jain S. Effect of CLU and PICALM polymorphisms on AD risk: A study from south India. Asian J Psychiatr. 2017 Jun;27:7-11. doi:10.1016/j.ajp.2016.12.017. Epub 2016 Dec 29. PubMed PMID: 28558900.

Thippeswamy H, Paul P, Purushottam M, Philip M, Jain S, Chandra PS. Estrogen pathway related genes and their association with risk of postpartum psychosis: A case control study. Asian J Psychiatr. 2017 Apr;26:82-85. doi:10.1016/j.ajp.2017.01.014. Epub 2017 Jan 19. PubMed PMID: 28483099.

Seshadri M, Banerjee D, Viswanath B, Ramakrishnan K, Purushottam M, Venkatasubramanian G, Jain S. Cellular models to study schizophrenia: A systematic review. Asian J Psychiatr. 2017 Feb;25:46-53. doi: 10.1016/j.ajp.2016.10.015. Epub 2016 Oct 17. Review. PubMed PMID: 28262173.

Velusamy T, Panneerselvam AS, Purushottam M, Anusuyadevi M, Pal PK, Jain S, Essa MM, Guillemin GJ, Kandasamy M. Protective Effect of Antioxidants on Neuronal Dysfunction and Plasticity in Huntington's Disease. Oxid Med Cell Longev.2017;2017:3279061. doi: 10.1155/2017/3279061. Epub 2017 Jan 12. Review. PubMed PMID: 28168008; PubMed Central PMCID: PMC5266860.

Vengalil S, Preethish-Kumar V, Polavarapu K, Mahadevappa M, Sekar D,Purushottam M, Thomas PT, Nashi S, Nalini A. Duchenne Muscular Dystrophy and Becker Muscular Dystrophy Confirmed by Multiplex Ligation-Dependent Probe Amplification: Genotype-Phenotype Correlation in a Large Cohort. J Clin Neurol. 2017 Jan;13(1):91-97. doi: 10.3988/jcn.2017.13.1.91. PubMed PMID: 28079318; PubMed Central PMCID: PMC5242159.

Babu RA, Paul P, Purushottam M, Srinivas D, Somanna S, Jain S. Differential expression levels of collagen 1A2, tissue inhibitor of metalloproteinase 4, and cathepsin B in intracranial aneurysms. Neurol India. 2016 Jul-Aug;64(4):663-70. doi: 10.4103/0028-3886.185350. PubMed PMID: 27381111.

Lenka A, Kamble NL, Sowmya V, Jhunjhunwala K, Yadav R, Netravathi M, Kandasamy M, Moily NS, Purushottam M, Jain S, Pal PK. Determinants of Onset of Huntington's Disease with Behavioral Symptoms: Insight from 92 Patients. J Huntingtons Dis. 2015;4(4):319-24. doi: 10.3233/JHD-150166. PubMed PMID: 26682993.

Vijayakumari AA, John JP, Halahalli HN, Paul P, Thirunavukkarasu P,Purushottam M, Jain S. Erratum: Figure Correction. Clin Psychopharmacol Neurosci. 2015 Aug 31;13(2):224-5. doi: 10.9758/cpn.2015.13.2.224. PubMed PMID: 26243855; PubMed Central PMCID: PMC4540037.

Mukherjee O, Das G, Sen S, Dutt A, Alladi S, Ghosh A. C9orf72 mutations may be rare in frontotemporal lobar degeneration patients in India. Amyotroph Lateral Scler Frontotemporal Degener. 2015;17(1-2):151-3. doi: 10.3109/21678421.2015.1074706. Epub 2015 Oct 14. PubMed PMID: 26465714.

Viswanath B, Jose SP, Squassina A, Thirthalli J, Purushottam M, Mukherjee O, Vladimirov V, Patrinos GP, Del Zompo M, Jain S. Cellular models to study bipolar disorder: A systematic review. J Affect Disord. 2015 Sep 15;184:36-50. doi: 10.1016/j.jad.2015.05.037. Epub 2015 May 28. Review. PubMed PMID: 26070045.

Vijayakumari AA, John JP, Halahalli HN, Paul P, Thirunavukkarasu P,Purushottam M, Jain S. Effect of polymorphisms of three genes mediating monoamine signalling on brain morphometry in schizophrenia and healthy subjects. ClinPsychopharmacol Neurosci. 2015 Apr 30;13(1):68-82. doi: 10.9758/cpn.2015.13.1.68. Erratum in: Clin Psychopharmacol Neurosci. 2015 Aug 31;13(2):224-5. PubMed PMID: 25912540; PubMed Central PMCID: PMC4423152.

Moily NS, Kota LN, Anjanappa RM, Venugopal S, Vaidyanathan R, Pal P,Purushottam M, Jain S, Kandasamy M. Trinucleotide repeats and haplotypes at the huntingtin locus in an Indian sample overlaps with European haplogroup a. PLoS Curr. 2014 Sep 24;6.pii:ecurrents.hd.  doi:10.1371/currents.hd.a3ad1a381ab1eed117675145318c9a80. PubMed PMID: 25642374; PubMed Central PMCID: PMC4205232.

Kota LN, Bharath S, Purushottam M, Moily NS, Sivakumar PT, Varghese M, Pal PK, Jain S. Reduced telomere length in neurodegenerative disorders may suggest shared biology. J Neuropsychiatry Clin Neurosci. 2015;27(2):e92-6. doi:10.1176/appi.neuropsych.13100240. Epub 2014 Dec 26. PubMed PMID: 25541866.

Kota LN, Bharath S, Purushottam M, Paul P, Sivakumar PT, Varghese M, Jain S. Reduced telomere length in subjects with dementia and diabetes mellitus type 2 is independent of apolipoprotein E4 genotype. Asian J Psychiatr. 2014 Dec;12:58-62. doi: 10.1016/j.ajp.2014.06.012. Epub 2014 Jun 30. PubMed PMID: 25440562.

Kota LN, Purushottam M, Moily NS, Jain S. Shortened telomere in unremitted schizophrenia. Psychiatry Clin Neurosci. 2015 May;69(5):292-7. doi:10.1111/pcn.12260. Epub 2015 Jan 12. PubMed PMID: 25430532.

Chandran V, Jhunjhunwala K, Purushottam M, Jain S, Pal PK. Multimodal evoked potentials in spinocerebellar ataxia types 1, 2, and 3. Ann Indian Acad Neurol.2014 Jul;17(3):321-4. doi: 10.4103/0972-2327.138519. PubMed PMID: 25221404;PubMed Central PMCID: PMC4162021.

Thirunavukkarasu P, Vijayakumari AA, John JP, Halahalli HN, Paul P, Sen S,Purushottam M, Jain S. An exploratory association study of the influence of dysbindin and neuregulin polymorphisms on brain morphometry in patients with schizophrenia and healthy subjects from South India. Asian J Psychiatr. 2014 Aug;10:62-8. doi: 10.1016/j.ajp.2014.04.002. Epub 2014 Apr 21. PubMed PMID: 25042954.

Jhunjhunwala K, Netravathi M, Purushottam M, Jain S, Pal PK. Profile of extrapyramidal manifestations in 85 patients with spinocerebellar ataxia type 1, 2 and 3. J Clin Neurosci. 2014 Jun;21(6):1002-6. doi: 10.1016/j.jocn.2013.10.021.Epub 2013 Dec 25. PubMed PMID: 24602359.

Viswanath B, Taj M J RJ, Purushottam M, Kandavel T, Shetty PH, Reddy YC, Jain S. No association between DRD4 gene and SRI treatment response in obsessive compulsive disorder: need for a novel approach. Asian J Psychiatr. 2013 Aug;6(4):347-8. doi: 10.1016/j.ajp.2013.03.003. Epub 2013 Apr 2. PubMed PMID:23810146.

Jhunjhunwala K, Prashanth DK, Netravathi M, Jain S, Purushottam M, Pal PK. Alterations in cortical excitability and central motor conduction time in spinocerebellar ataxias 1, 2 and 3: a comparative study. Parkinsonism Relat Disord. 2013 Mar;19(3):306-11. doi: 10.1016/j.parkreldis.2012.11.002. Epub 2012 Dec 3. PubMed PMID: 23219306.

Taj M J RJ, Viswanath B, Purushottam M, Kandavel T, Janardhan Reddy YC, Jain S. DRD4 gene and obsessive compulsive disorder: do symptom dimensions have specific genetic correlates? Prog Neuropsychopharmacol Biol Psychiatry. 2013 Mar 5;41:18-23. doi: 10.1016/j.pnpbp.2012.10.023. Epub 2012 Nov 2. PubMed PMID:23127570.

Gupta M, Jain S, Moily NS, Kaur H, Jajodia A, Purushottam M, Kukreti R. Genetic studies indicate a potential target 5-HTR(3B) for drug therapy in schizophrenia patients. Am J Med Genet B Neuropsychiatr Genet. 2012 Dec;159B(8):1006-8. doi: 10.1002/ajmg.b.32105. Epub 2012 Oct 17. PubMed PMID:23076996.

Kota LN, Shankarappa BM, Shivakumar P, Sadanand S, Bagepally BS, Krishnappa SB, Purushottam M, Sivakumar PT, Jain S, Varghese M, Bharath S. Dementia and diabetes mellitus: association with apolipoprotein e4 polymorphism from a hospital in southern India. Int J Alzheimers Dis. 2012;2012:702972. doi: 10.1155/2012/702972. Epub 2012 Jun 3. PubMed PMID: 22701197; PubMed Central PMCID: PMC3371687.

Ram Murthy A, Purushottam M, Kiran Kumar HB, ValliKiran M, Krishna N, Jayramu Sriharsha K, Janardhan Reddy YC, Ghosh S, Jain S. Gender-specific association of TSNAX/DISC1 locus for schizophrenia and bipolar affective disorder in South Indian population. J Hum Genet. 2012 Aug;57(8):523-30. doi: 10.1038/jhg.2012.62. Epub 2012 Jun 7. PubMed PMID: 22673686.

Bagepally BS, Halahalli HN, John JP, Kota L, Purushottam M, Mukherjee O, Sivakumar PT, Bharath S, Jain S, Varghese M. Apolipoprotein E4 and brain white matter integrity in Alzheimer's disease: tract-based spatial statistics study under 3-Tesla MRI. Neurodegener Dis. 2012;10(1-4):145-8. doi: 10.1159/000334761. Epub 2012 Jan 21. PubMed PMID: 22269984.

Sureshkumar R, Bharath S, Jain S, Prakash O, Purushottam M, Thennarasu K, Mukherjee O, Sivakumar PT, Varghese M. ApoE4 and late onset depression in Indian population. J Affect Disord. 2012 Feb;136(3):244-8. doi: 10.1016/j.jad.2011.12.022. Epub 2012 Jan 5. PubMed PMID: 22226379.

Yadav R, Pal PK, Krishna N, Amar BR, Jain S, Purushottam M. Electrophysiological evaluation of spinocerebellar ataxias 1, 2 and 3. J Neurol Sci. 2012 Jan 15;312(1-2):142-5. doi: 10.1016/j.jns.2011.07.051. Epub 2011 Aug 31. PubMed PMID: 21880333.

Goel G, Pal PK, Ravishankar S, Venkatasubramanian G, Jayakumar PN, Krishna N, Purushottam M, Saini J, Faruq M, Mukherji M, Jain S. Gray matter volume deficits in spinocerebellar ataxia: an optimized voxel based morphometric study. Parkinsonism Relat Disord. 2011 Aug;17(7):521-7. doi: 10.1016/j.parkreldis.2011.04.008. Epub 2011 May 20. PubMed PMID: 21600833.

Bharath S, Purushottam M, Mukherjee O, Bagepally BS, Prakash O, Kota L, Krishnappa SB, Sivakumar PT, Jain S, Varghese M. Apolipoprotein E polymorphism and dementia: a hospital-based study from southern India. Dement Geriatr Cogn Disord. 2010;30(6):455-60. doi: 10.1159/000322093. Epub 2011 Jan 20. PubMed PMID:21252538.

Tibrewal P, Kumar HB, Shubha GN, Subhashree D, Purushottam M, Thennarasu K, Reddy YC, Jain S. Association of serotonin transporter gene polymorphisms with obsessive-compulsive disorder (OCD) in a south Indian population. Indian J Med Res. 2010 Dec;132:690-5. PubMed PMID: 21245616; PubMed Central PMCID: PMC3102456.